INTRODUCTION: Are there really miracle weight loss drugs?


"I have always felt insecure about my body, but I never felt strange about that. All the women I know feel insecure about their bodies”, NOW intern.

“Whenever I come home for a visit from college, the first thing my dad comments on is whether or not I have gained weight, as if that is what matters the most. I try not to pay attention to it, but it has made me feel pretty self-conscious about my body," NOW intern.

…13-year-old girl…crying herself to sleep, "I'm so fat…my stomach sticks out! I know people aren't supposed to judge you by the way you look, but they do! They always do!"

Are there miracle weight loss drugs? If you are the maker of Metabolife, a “miracle” weight loss pill, who made approximately $93 million in three years, or Glaxo, the maker of Alli, who anticipates $1.5 billion in sales, your answer may be a positive one. And it's no wonder...Weight Watchers posted a $57.4 million dollar profit during the first quarter of 2008 and Jenny Craig posted a $20.1 billion dollar profit during the first quarter of 2007. There's a lot of money to be made when we feel bad about ourselves.

Being overweight carries with it a terrible stigma. And when overweight people are the target of endless, merciless jokes, it’s no wonder that “miracle” weight loss drugs are making obscene profits. For example, a lawmaker in Mississippi in 2008 proposed a bill prohibiting overweight people from dining out in restaurants. Newsweek published on an article dated May 18, 2008, “Global Warming: It’s Fat People’s Fault”. When someone is overweight, even if by a few pounds, most will do anything to lose the weight, even if it damages one’s health. In 1998, Fen-Phen was known to damage heart valves yet continued to sell as a weight loss product. A 41 year old woman took Fen-Phen for about 3 months, she was diagnosed with primary pulmonary hypertension years later after discontinuing the drug.
http://www.lawyersandsettlements.com/articles/00286/fen_phen.html

The challenge with weight loss drugs is that they are not regulated like prescription drugs. This means that that many of these products can put additives in their products that may not be listed on the label, hence causing unseen damage. The Mayo clinic lists some of the ingredients that are commonly found in miracle weight loss drugs, what they’re from and what they do to the body. Both nurses and consumers need to be aware of these issues regarding weight loss drugs in order to ensure safety and well-being of one's health.

Thankfully, there are ways to lose weight safely and web sites that support this. Weightlossforall.com provides good advice for people who want to safely lose weight. The FDA has published an on-line guide on their web site about losing weight safely and effectively.

Are there really “miracle” weight loss drugs? Unfortunately, the answer leans towards no. The most effective way to lose weight is through lifestyle change: exercise and eating a healthful diet.

In this blog, we discuss the issue of miracle weight loss drugs in detail - the who, what, where, when, why, and how. Why is this a hot issue? How did it begin? Who should care? Who is involved? What is the big controversy? What are the news sources and experts saying about this issue? Why should nurses and consumers be educated? We have done thorough research from scientific journals (both older and recent) on the UTA Library Database as well as the FDA website so that you could get the entire scoop over the issue of miracle weight loss drugs.

http://www.fda.gov/bbs/topics/NEWS/2008/NEW01933.html
http://www.fda.gov/opacom/lowlit/weightls.html.
http://www.mayoclinic.com/health/weight-loss/HQ01160.
http://www.fda.gov/bbs/topics/NEWS/2008/NEW01933.html
http://junkfoodscience.blogspot.com/2008/01/no-fat-people-allowed-only-slim-will-be.html
http://www.blog.newsweek.com/blogs/labnotes/archive/2008/05/16/global-warming-it-s-fat-people-s-fault.aspx
http://www.fen-phen-injury.com/texas.htm

Sunday, February 22, 2009

Scientific Data: The straight dope on weight-loss drugs

Despite abundant advertising hype, no drug (and no "natural" herb) offers a magic bullet against obesity. There are some new drugs though that may provide support in a balanced weight-loss program.

"Although Americans would like to have a pill to cure obesity, the best that will ever be available is something that will contribute to a lifestyle effort and make it less of a struggle," says Madelyn Fernstrom, PhD, director of the Weight Management Center of the University of Pittsburgh in Pennsylvania.

By Prescription Only
The three most-prescribed prescription drugs are:
* Xenical (orlistat), approved by the Food and Drug Administration (FDA) in 1999. It interferes with the digestion of fats and prevents about 30 percent of the fat that you eat from being absorbed by your body.
* Meridia (sibutramine), approved in 1997. It boosts the levels of two neurotransmitters--norepinephrine and serotonin--in your brain to moderate hunger cravings and give you a feeling of fullness.
* Phentermine (available under Ionamin and Adipex-P), approved in 1957. Phentermine suppresses appetite by boosting norepinephrine levels. It is approved only for short-term use.

Over-The-Counter Options
The only FDA approved OTC weight-loss drug is Alli, which only works if the consumers follow a strict regimen of diet and exercise.

Beware Herbal Remedies
For the most part, the only diet medications now available without a prescription are herbal and other "natural" preparations. Dietary supplement manufacturers do not have to tell the FDA about adverse effects, and the product labels aren't good either. Conventional physicians and researchers consider most of them useless and some of them dangerous. "Herbal remedies are not well supported at all by clinical-trial data," says Belinda O'Connell, MS, RD, LD, a clinical dietitian at the International Diabetes Center in Minneapolis, Minn.

"Although they may look like medicine, herbal weight-loss remedies are neither effective nor - in some cases - safe," says Madelyn Fernstrom, PhD, of the University of Pittsburgh.

The FDA believes these people were wasting their money and risking their health. "Only a few herbal weight-loss remedies have been tested in clinical trials, generally with no evidence of benefit," notes Samuel Klein, MD, of Washington University in St. Louis, Mo.

For example, Ephedra's potential side effects can include high blood pressure, irregular heartbeat, stroke, and seizures. A scientific measurement of the ingredients of 20 ephedra brands found that in half, the label was wrong by more than 20 percent. One brand had 10 times the amount of ephedrine alkaloids stated on the label. Another had none at all.

"Laxatives and diuretics may make people think they have lost weight, but it's only water weight," says Fernstrom. "They're not thinner, just dehydrated."

CHECK OUT THE FoxNewsChannel VIDEO HERE as well as the video posted below!



Fentress, D., & Agnew, B., from Diabetes Forecast, 4/2002, Vol. 55 Issue 4, 51-55.

16 comments:

  1. Catchy title :-D
    This gives a clear understanding of the various types of weight loss drugs out there.

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  2. It also shows the obsession everyone has with weight. Not only have we become materialistic but we have become self conscious about how our outside appearance is viewed by others. EP

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  3. It’s insane how many weight loss drugs there are. Think about shows like “The Biggest Loser.” That’s all I have to say.

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  4. If there are so many drugs for weight loss, why then does people risk having surgery just to loose weight, and they have to pay on top of that.

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  5. The drive for perfection/control starts very young and is continually fueled by all forms of media. In the matter of weight "control", it does not stop. Even the elderly woman who has never had to face the weight-loss conundrum is soon hit with weighty issues related to body changes with menopause and can fall victim to the hype to "look your best, be youthful, lose that unwanted belly bulge", etc. Advertising is slick and makes it's money on promoting what are often falsehoods disguised as truth. Good points on health fraud and monitoring what goes into the body! Be natural, while not regarded as beautiful in the western world has alot going for it in terms of health when combined with sensible eating and increased activity.

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  6. Great job, I didn't see any thing that went against known medical knowledge. I especially found the herbal supplement subject interesting as it has been a topic of interest with my peers of late. Once again the hype created by media and word of mouth seems to outweigh the value of good solid research, how unfortunate. I agree wholeheartedly with the statement that the best way to lose weight is lifestyle change, even people with poor metabolism can stay in shape if their diet and exercise habits are designated appropriately. Once again, good job guys!

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  7. I think Alli is the safest weight loss drug out there, but is it really worth it? It might not be effective for everyone, but for those who really want to lose weight, it’s probably worth the shot to try.

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  8. I’ve read a lot of success stories in which people on Alli said that the drug works as long as you don’t eat fatty foods. Well, why not just eat healthy in the first place and try to exercise as much as you can? How exactly does Alli work? I don’t want to sound harsh, but I cannot understand the significance of some weight loss pill because I’ve been trying to eat healthy and in proportional amounts ever since I was a child, and I even play soccer. I do understand that being overweight can be hereditary, but it runs in my family and I do not have a weight problem because of my lifestyle.

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  9. Maybe these pills help in addition to diet and exercise. Once you start losing some weight, then your friends and family will start giving you compliments and it then gets easier and easier to demonstrate self control and eat less.

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  10. If I were overweight, I'd choose Alli b/c it has been proven to be the safest weight loss drug out there. Also, the TV ads even show wynonna judd as the spokesperson for Alli, which I think is a good sign b/c top-notch, respectable celebrities would only advocate something that would be of great benefit to all.

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  11. You would think that herbal supplements would be the safest, but maybe it's better to just eat fresh garlic, ginger, and herbs rather than pop a pill containing those ingredients.

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  12. There are so many types of congenital heart diseases that infants are unfortunately born with. That's because of natural processes in the body though. It can't really be controlled. On the other hand, taking pills that can lead to heart defects CAN be controlled. It's a choice.
    -AK

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  13. Let's not blame the overweight Americans for wanting a miracle weight loss pill... everyone wants a "miracle" something to make ease of their lives in one way or another... It's all the result of living in a high-tech society.

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  14. Lots of people eat fresh ginger, garlic, and herbs, which are healthy with many benefits. So of course people are gonna think that herbal weight loss drugs are healthy also... it's very deceiving on behalf of those production companies.

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  15. In this days all the people want to lose weight fast and for that they will take weight loss medicine.

    diet drops & hcg diet program

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  16. I have a big love about reading to collect useful information about weight loss drugs.And today I have found this blog.Thank you so much for what you have shared.
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